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Since B6 turns tryptophan into niacin quickly, and doesn't let it turn into serotonin, I would think high B6 levels would also cause depression.
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In the first set of experiments, we used a double-blind prospective design to investigate the psychological consequences of illness in two models: (1) vaccination of teenage girls with live attenuated rubella virus, and (2) lipopolysaccharide (LPS) administration in healthy male volunteers.
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